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Researchers tested several different forms of tyrosine delivered orally to mice to document which forms were superior for increasing brain levels of tyrosine

Further, we compared the extracted mutational signatures with known SBS signatures in the COSMIC database, ultimately identifying SBS4 (smoking related), SBS5 (unknown etiology), SBS13 (APOBEC cytidine deaminase related), SBS40 (unknown etiology), and SBS60 (sequencing artefact) signatures (Fig