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Zeng Z, Samudio IJ, Zhang W, Estrov Z, Pelicano H, Harris D, Frolova O, Hail N, Jr, Chen W, Kornblau SM, Huang P, Lu Y, Mills GB, Andreeff M , Konopleva M

133 In summary, inflammatory signals and metabolic imbalance within the context of gut barrier impairment and microbiota dysbiosis exert a long-range effect on skeletal muscle homeostasis, exacerbating their negative nitrogen balance, wherein the synthesis of skeletal muscle proteins falls below their breakdown rates

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MDA crosses the cell membrane into the extracellular compartment

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