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10.1002/jor.1100170607 125 IwahashiM.MatsuzakiH.TokuhashiY.WakabayashiK.UematsuY

To better understand the pathophysiology of this complex process, this review aims to outline the potential processes and possible therapeutic strategies for intestinal damage after HS in recent years

Melatonin signaling pathway Melatonin, a hormone produced by the pineal gland that plays a pivotal role in regulating circadian rhythms, significantly decreases in level as age progresses, manifesting as a deterioration of circadian rhythmicity