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The infiltration of neutrophils is commonly seen in all types of liver diseases

Crystal structures of Sj26GST in complex with glutathione sulfonate (Sj26GSTSLF), S-hexyl glutathione (Sj26GSTHEX), and S-2-iodobenzyl glutathione (Sj26GSTIBZ) allow characterization of the electrophile binding site (H site) of Sj26GST

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Future studies need to further integrate metabolomics, single-cell transcriptomics, and clinical trial data to clarify the functions of different amino acid pathways across distinct RA subtypes and disease stages, thereby laying the foundation for precision metabolism-targeted intervention strategies