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In contrast, zVAD had a minimal effect on ibrutinib-induced cell death, suggesting that apoptosis plays only a minor role, whereas ferroptosis contributes more prominently to the cytotoxic effects of ibrutinib (Fig

Innate and adaptive immune responses against coronavirus

In a study by Pandian JD et al., 314 stroke patients were interviewed, of which 230 (73.2%) were men

Mechanistically, the inflammation mediated by the Caspase-1/NLRP3, TLR4/NLRP3, MAPK/NF-B/NLRP3, and Nrf2/HO-1/NLRP3 pathways have been implicated in the pathogenesis and progression of AP (Papantoniou et al., 2024), highlighting their potential as therapeutic targets