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TNF-a) involve in apoptosis pathway and a possible inducer to P53 parenchymal cells, it also the factor which is responsible for the damage of the parenchyma of the lung due to the failed remodeling process (Yadegari et al

Wilcoxon signed-rank test or the paired t-test was used to analyze changes from the baseline to the endpoints

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For polymorphisms in the and GSTT1 genes, the results did not indicate an increased risk of developing DM or DN [30]