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however, it seems that an increased risk of HF does not increase the risk of death or cardiovascular events following HF

It is important to note that the dual or Janus-faced nature of the AhR signaling pathway is a universal feature of its biological function and has been described in multiple tissues

The miR-21 overexpression decreased SOX2 expression in SS-AF-MSCs, leading to reduced proliferation, clonogenicity, and cell cycle arrest