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FIGURE 2 2.2 Regulation of inflammatory responses by EVs in IBD In general, the anti-inflammatory or pro-inflammatory functions of EVs are determined by their different cellular origins and cargos (Li et al., 2023)

In other diseases, inhibition of ACSL4 to reduce lipid peroxides and ferroptosis is a possible therapeutic strategy, but there is currently no similar study in preclinical studies of Friedreichs Ataxia