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The overall lower total organic content for the FA-conjugated material (30%) compared with the non-conjugated drug-loaded SBA-15 (50%) implies that conjugation reduced the amount of physically adsorbed (free) drug for example by replacing weakly adsorbed drug with covalently tethered folic-aciddrug species or by additional washing steps removing unbound drug

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Probabilistic stimulation atlases (PSAs) Individual structural MR images of each patient were coaligned with a 100 50 80 mm MNI standard space with an isotropic voxel of 0.1 mm