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Mice were treated by estradiol alone daily for 12 days (controls) or in combination with resveratrol daily for 20 days (controls)

doi: 10.3390/biomedicines8100390

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However, an additional defatting step is often performed to further decrease the fat content to 0.3-0.5% in order to increase membrane separation performance or to prevent an irreversible fouling or clugging of ion-exchange resins with polar lipids