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Cisplatin is one of the most widely used chemotherapeutic agents for the treatment of a broad spectrum of cancers 17,18,19

Since then, a large number of organochlorines produced through geogenic processes such as volcanic activity and forest fires, and biogenic sources, were reported (Moore, 2003), and biosynthesis of halogenated secondary metabolites by bacteria, fungi, plants and animals, especially in the marine environment (van Pe and Patallo, 2006

Numerous protein, gene, and cell-based therapeutics have been extensively studied in models of liver failure and peripheral artery disease before being introduced into clinical trials

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Effect of nanoemulsion modification with chitosan and sodium alginate on the topical delivery and efficacy of the cytotoxic agent piplartine in 2D and 3D skin cancer models