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Diagnosis is typically performed with blood tests, urine copper tests, liver biopsy (in some cases), genetic testing, and eye examination

Conservative treatments include medications (e.g., steroids, vitamin B12, non-steroidal anti-inflammatory drugs [NSAID], and gabapentin), splint, and physiotherapy 4

These directly inhibit mitochondrial complex III function, reducing ATP synthesis and promoting the release of apoptotic factors

Flushing and triggers Temporary redness from heat, spicy food, alcohol, exercise, or strong emotions is your vascular system doing its job, widening vessels to release heat

The end stage of CKD, renal fibrosis, is the result of an injury that leads to the production of ECM components