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Bioinformatics (2012) 28(6):8823

Additionally, no new nanomedicines have been approved by the Food and Drug Administration (FDA) or European Medicines Agency (EMA) for RA between 2023 and 2025, highlighting significant gaps in translating laboratory innovations into clinical practice (54)

DPP1 inhibitors reduce mucus production by alleviating inflammatory responses, while mucolytic agents primarily improve clearance efficiency of already produced mucus (Yang et al., 2019)