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The guts both a site of mycotoxin damage and a critical pathway for elimination

Clinically prevalent mutations in Mycobacterium tuberculosis alter propionate metabolism and mediate multidrug tolerance

Ferroptosis is negatively regulated by the enzymatic activity of GPX4, and increasing attention to possible ways of inhibiting this cell death modality are needed ( In order to test if our new activator could have a beneficial effect in the context of inhibiting cell death, we evaluated compound 102 for its ability to prevent erastin-induced ferroptosis