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Consequently, the implementation of standardised purification procedures and compositional profiling is essential before CQDs synthesised via green routes can be compared meaningfully between studies [168, 169]

SIRT1 deacetylates and activates key transcription factors such as FOXO and PGC-1 that promote neuronal survival and mitochondrial biogenesis, while SIRT3 enhances mitochondrial function and reduces oxidative stress in neurons

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