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'It's an area in which there is insufficient evidence and that is why we want to investigate how they modify smoking, whether the e-cigarette legislation to protect consumers and rules to protect non-users such as child-proof caps, actually have an impact on a population basis.' Even though Europe-wide legislation is in place, there are differences in the levels of regulation, for example on plain packaging or e-cigarette sales, between Member States, which gives the study a 'natural randomisation' which will be useful for the researchers, he says

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