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A single missed dose has minimal impact on overall results

It is the reason the FDA's career scientists spent months reviewing the evidence and arrived at a unanimous negative recommendation before a panel whose composition may not be positioned to weigh that evidence independently

Reference: Goldstein AL et al

Topical gels or vaginal creams offer noninvasive local exposure with lower systemic levels, but penetration to target layers can be inconsistent

After mcl transaction bpc 157 was effective in rats when given once daily intraperitoneally (10 microg or 10 ng/kg) or locally as a thin layer (1.0 microg dissolved in distilled water/g commercial neutral cream) at the site of injury, first application 30 min after surgery and the final application 24 h before sacrifice