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The ability of the VLNC intervention to promote smoking cessation was specifically tested at week 12 when participants were offered $100 to abstain from smoking for 24 hours, a modest goal given that most smokers who abstain for 24 hours relapse, and smokers do not get such offers in real life

In one study, identifying the effects of naltrexone for smoking cessation, the use of naltrexone (vs placebo) has resulted in increased quit rates, attenuated smoking urge, and reduced weight gain

The formation of kidney stones can be prevented by undertaking certain lifestyle changes

Initiating naltrexone treatment during pregnancy is generally not recommended, especially for individuals currently using opioids, as it requires complete detoxification, which carries risks for both the mother and fetus

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