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Free radicals and antioxidants in human health

[DOI] [PMC free article] [PubMed] [Google Scholar] 143.Aromolaran K.A., Goldstein P.A

153 Allicin also demonstrates hepatoprotective effects against APAP-induced liver injury by attenuating oxidative stress and inhibiting the NLRP3 inflammasome pathway, effectively preventing the release of proinflammatory cytokines

FABP5 may interact with PPAR/ or other antioxidant transcriptional regulators such as NRF2 to modulate transcriptional networks, thereby indirectly repressing GPX4 expression [7, 8]

Obesity is actually associated with increased biliary cholesterol excretion due to upregulated hepatic cholesterol synthesis, which supersaturates the bile and increases the risk of cholesterol gallstone formation