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Clin Sci 131:981990 Berridge MJ, Bootman MD, Roderick HL (2003) Calcium signalling: dynamics, homeostasis and remodelling

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3 Results 3.1 Effects of nicotine salts on dopamine (DA) release in the nucleus accumbens (NAc) Nicotine increases the release of DA from the NAc

Some research now suggests that e-cigarettes may be a gateway drug among youths, meaning that as we see an increase in the number of children vaping, opioid use among youths is also likely to rise