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now the study period has been extended to 40 years (1951-91) and covers over 20 000 deaths Overall, the excess mortality of cigarette smokers was approximately twice as extreme in the second half as in the first half of this study Twenty five causes of death were significantly associated with cigarette smoking (24 positively and one negatively) Even in middle age stopping smoking substantially increased the subsequent expectation of life - and those who stopped before 35 years of age had an expectation of life that was not significantly different from that of non-smokers Introduction After the two large case-control studies of 1950 that showed lung cancer to be closely related to smoking,1,2 prospective studies were needed that could determine which other diseases were also related to the habit

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We were obsessed with her, said Romy Mars, who was there with a friend

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