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Fluid retention and edema: During treatment with glucocorticoids and diclofenac, edema and fluid retention have been observed so the formula must be used with caution in patients with a history of decompensation, hypertension or other factors predisposing to fluid retention

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doi:10.1016/j.brs.2020.11.014

The most commonly described benefits include increased energy that feels steady rather than jittery, improved mental clarity and focus, better mood regulation, and a general sense of feeling more like themselves again

These medications are often topical, but oral treatment is available for more serious cases