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If lumps persist, worsen, or show signs of infection, consult your GP or prescribing clinician

It is written strictly for research-context decision support: nothing here is a recommendation for human use, and all dose figures cited are reproduced from published animal and in vitro work for protocol-design reference only

Starting with lower doses and increasing gradually allows assessment of personal tolerance before committing to full therapeutic doses

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The knockout of JAM-A, one of the key structural components of tight junctions, causes mild colitis in mice, and these mice show the increased susceptibility to DSS induced IBD (Laukoetter et al., 2007, Serek and Oleksy-Wawrzyniak, 2021)