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The slices were incubated a further 6 h to allow for internalization, and then stripped with proteinase K and then fixed with 4% PFA, as described in detail in the figure legend

C KEGG pathway enrichment analysis of the DEGs shown as a circus plot

Dried samples were dissolved in 20 l 0.1% formic acid, sonicated for 30 s and centrifuged for 10 min at 16,100 g

The nanosheet surface is coated with polydopamine and chitosan, targeting breast cancer cells via folic acid and encapsulating drug 5-fluorouracil to achieve a synergistic effect between chemotherapy and photothermal therapy

Vitamin B12 is an essential vitamin required for metabolic functions, including fat and carbohydrate metabolism and protein synthesis