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The most important minerals exhibiting antioxidant activity are selenium and zinc

Behavior problems in the pervasive developmental delay or autism-spectrum range may be seen among other multi-system manifestations in primary mitochondrial disease, although recent debate has erupted as to whether autism can be an isolated manifestation of mitochondrial disease (19-21)

An uncoupled eNOS enzyme stops producing nitric oxide and instead generates superoxide directly. That superoxide combines with the remaining nitric oxide to produce more peroxynitrite