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The early identification of SCD and MCI may offer a crucial window for intervention

The foundational mechanism papers from the Washington State University lab were retracted in April 2025 after a misconduct finding of image manipulation

Of these, 35 were preclinical animal studies and only one represented a human clinical investigation

However, the survival benefit of sorafenib was disappointing in clinical trials, owing to its low response rate and short effective duration, caused by intrinsic and acquired resistance (Cheng et al., 2009