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If the rat chow diet was supplemented by N -acetylcysteine, noted elsewhere in this article to provide the rate-limiting reagent for glutathione synthesis and protect against A42-associated OS in vivo (147), OS was significantly reduced

[30] Lo que implica una excrecin por las heces de entre un 80 a un 100 % de la dosis oral de esta vitamina, en comparacin con el 30 a 60 % de excrecin en heces que se ve en individuos con factor intrnseco adecuado

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Traitement de l'anmie pernicieuse [modifier | modifier le code] Traitement substitutif spcifique la vitamine B 12 Essentiel et lui seul suffisant, le traitement substitutif la vitamine B 12 doit comporter un traitement d'attaque (d'emble doses importantes), visant recharger les rserves [17] , enrayer les progrs de l'atteinte nerveuse et rparer l'anmie, puis un traitement d'entretien destin durer toute la vie restante du patient