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Ziqiang Meng, Guohua Qin, Bo Zhang, Juli Bai

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CAFs are also involved in tumour immune evasion through interactions with MDSCs, which exert immunosuppressive functions and affect T cell proliferation, and with dendritic cells, leading to the downregulation of their HLA molecules 167,168,169

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Therefore, studying the parameters of the SPM of specific zones, their impact on the human body, and identifying subtle cellular mechanisms can help in the development of new strategies for the prevention of environmentally dependent pathologies