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More important, their results revealed that ACN can significantly decrease MDA levels which is a biomarker for lipid peroxidation secondary to generation of ROS and reduce inflammation by preventing upregulation of pro-inflammatory cytokines, such as Interleukin 6 (IL-6), Interleukin 1b (IL-1b) and chemokine (C-X-C motif) receptor 2 (Cxcr2) (Donepudi et al., 2011)

The His-tagged proteins were purified using Ni + -affinity chromatography and protein concentration was determined using the bicinchoninic acid (BCA) method

The researchers found that Ginkgolide B enhances the expression of neuronal markers and supports the maturation of neural stem cells, suggesting its potential in promoting neurogenesis and repairing neural damage (Li et al

Due to the lack of DNA repair machinery within the mitochondria, cisplatin-induced mitochondrial DNA damage could not be repaired, which led to the release of cytochrome c from damaged mitochondria and induced apoptosis in DRG neurons (Gill and Windebank, 1998

The selenoprotein family composes of proteins with diverse functionality, however, several are classified as antioxidant enzymes (Reeves, 2009) and this function is of particular importance for this KER