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MTHFR Gene Variant Testing Explained - What It Shows and Why You Should Look Beyond It Testing MTHFR is straightforward: a cheek swab or blood test looks for C677T and A1298C

Its advantage lies in its multi-target mechanism of action, which can simultaneously act on multiple pathological links such as free radicals, inflammatory factors and glycation reaction, thus playing a comprehensive protective role in a variety of diseases

Supplementation may address this gap, particularly for those on restrictive diets or with higher metabolic demands during weight loss

Phytochem Anal 24:319328 Sonawane PD, Pollier J, Panda S et al (2016) Plant cholesterol biosynthetic pathway overlaps with phytosterol metabolism