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To protect these cell structures, some enzymatic antioxidants are produced upon exposure to ROS, including a catalase that breaks down hydrogen peroxide (H 2 O 2 ) into water and oxygen 4

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Back to Journals Clinical, Cosmetic and Investigational Dermatology Volume 19 Danggui Buxue Decoction Attenuates H 2 O 2 -Induced HaCaT Cells by Modulating SOD2 Antioxidant and P21 Senescence Pathways Authors Chen X, Zheng H , Cheng H , Wu J, Wang G, Liu M , Yang Q , Yang Q Received 8 December 2025 Accepted for publication 9 March 2026 Published 13 March 2026 Volume 2026:19 587240 DOI Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Prof

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