DBCO-Dap(m-PEG4)-Val-Cit-PAB deuterium-labeled-ketone 5-(and-6)-carboxyl-2

5-(and-6)-carboxyl-2

349 Purity (HPLC) >= 95% Solubility DMSO

542 SMILES CC(C)N1N=C(C)N=C1C1=CN2CCOC3=CC(=CC=C3C2=N1)C1=CN(N=C1)C(C)(C)C(N)=O Purity (HPLC) >= 95% Physical Appearance White solid Solubility DMSO

S)-AHPC-CO-PEG6-propargyl Synonyms CAS Number n/a Related CAS Molecular Formula C38H56N4O10S Molecular Weight 760

Nature Chem 5

DBCO-Dap(m-PEG4)-Val-Cit-PAB deuterium-labeled-ketone 5-(and-6)-carboxyl-2SOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a DBCO Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG,