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A good example of this is given by flutamide, an antiandrogen used in the treatment of prostatic carcinoma, which undergoes substantial metabolism in vivo with hydrolysis of the amide bond liberating 3-trifluoromethyl-4-nitroaniline

Furthermore, understanding how this metabolites physiology level changes in connection to other aspects of clinical normalcy may be interesting (196)

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Zhong X, Tang T-T, Zhang Y, Xue D-D, Shen A-R, Li N, et al