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A recent study showed that the HSV-1 host/pathogen interactome is highly concentrated in susceptibility genes for neurological disorders, primarily for MS, with enrichment values at 4-fold, suggesting that HSV-1 may contribute to several diseases in a gene-dependent manner by modulating essential pathways involved in the onset or severity of this neurodegenerative disease (Carter, On the other hand, microorganisms may also contribute to the pathogenesis of MS by inducing the activation and clonal expansion of self-reactive lymphocytes through molecular mimicry (Wucherpfennig and Strominger, 1995)

This provided further corroboration that genes identified by our screen are not generally required for intestinal gene expression or GFP stability

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Human-like collagen protein-coated magnetic nanoparticles with high magnetic hyperthermia performance and improved biocompatibility

doi: 10.1186/s40168-016-0178-x 229 WangJYangYShaoFMengYGuoDHeJet al