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Reconstitution: Mix with bacteriostatic water or sterile saline before use

The moment you introduce a liquid, youre reawakening the compound, making it biologically active and, simultaneously, vulnerable

10.1371/journal.pone.0062687 130 SepulvedaP

May your semaglutide stay potent, your refrigerator stay reliable, and your protocols stay on track.

Muco-penetrating approaches that have made it to the clinic include PEGylated adrenomedullin (NCT04417036, phase II of BAY1097761 for acute respiratory distress syndrome), amikacin liposomes (FDA-approved for mycobacterium infections therapy) and ciprofloxacin liposomes (NCT02104245, phase III of ciprofloxacin liposomes for non-cystic fibrosis bronchiectasis), all showing better penetration and retention in the airways during delivery (Table 3)