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These compounds have demonstrated promising anti-cancer properties, including tumor immunity enhancement, reversal of multidrug resistance, regulation of autophagy and ferroptosis, and antiproliferative, pro-apoptotic, and anti-metastatic effects, both in vitro and in vivo (Fig

Semaglutide (Wegovy) was FDA-approved specifically for weight management, and it has shown substantial weight loss benefits in individuals with obesity

Gene counts and UMI counts were acquired via featureCounts software

Because patients with COVID-19 have evidence of systemic inflammation, often have their course complicated by acute respiratory distress syndrome, and may have respiratory mucus buildup limiting adequate airflow, systemic or aerosolized N -acetylcysteine (or both) may be beneficial in this specific patient population

(European Food Safety Authority, 2006)