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The various forms of injectable B12 have slightly different properties that impact how you might respond: Cyanocobalamin is the most synthesized and stable type but has to convert to active forms

The Rule: Absolutely no alcohol of any kindincluding beer, wine, or spirits

This is because heat, moisture, and light can all contribute to the degradation of the vitamin and reduce its effectiveness

This has clinical relevance, as both insulin and free IGF-1 levels are increased in individuals with obesity, and T cells have been found to dominate peripheral inflammation in obesity in human studies, with Th17 cells having a particularly prominent role 30,31,32

Am J Clin Nutr 2018;108:525-31