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Muscle immobilization and remobilization downregulates PGC-1 signaling and the mitochondrial biogenesis pathway

This work was supported by the Fundamental Research Program of Shanxi Province (202403021212266) and the Changzhi Medical College Research Initiation Funds for PhD (BS202317)

According to the SmPCs, semaglutide should be discontinued at least 2 months before a planned pregnancy, and both medications should be stopped immediately if pregnancy occurs