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QZ contributed to the conception of the study and revised the manuscript provided guidance to the manuscript

Some sensor proteins bind DAMPs or PAMPs directly, such as AIM2, which recognizes viral or bacterial double-stranded DNA [303, 304]

Looking at the X-ray crystal structure of auranofin-trypanothione reductase-NADPH complex, gold was found bound to two cysteine residues (Cys52 and Cys57) while the sugar moiety bound to the docking site from another parasite, L

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sativa oil not only has been shown to inhibit enzymes such as acetylcholinesterase (AChE), it also affects brain tumor necrosis factor-alpha and glutathione, so it might be a promising neuroprotective agent