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Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial Confident characterization and identification of glucuronide metabolites using diagnostic fragments from electron activated dissociation (EAD) does lidocaine use glutathione or glucuronidation Medicinal chemistry on metabolism(Phase I & Phase II Reactions) Chronic alcoholism lowers the Metabolism of acetaminophen in humans. The three pathways, (a) Download Scientific Diagram Mechanism of the glucuronidation reaction catalyzed by Download Scientific Diagram

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