Phthalimidinoglutarimide-propargyl-C1-OH deuterium-labeled-carboxylic ester 95 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCOCCOCCOCCOCCOCCOCCO)C(C)(C)C)C=C1 Purity (HPLC)

95 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCOCCOCCOCCOCCOCCOCCO)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name Phthalimidinoglutarimide-C4-OH Synonyms Phthalimidinoglutarimide-4'-C4-OH CAS Number 2207541-24-8 Related CAS Molecular Formula C17H20N2O4 Molecular Weight 316

Product Name 1-bromo-2-(methoxy-d3)benzene Synonyms 1-bromo-2-(²H3)methoxybenzene CAS Number 892397-56-7 Related CAS Molecular Formula C7H7BrO Molecular Weight 190

S)-AHPC-CO-PEG5-propargyl Synonyms CAS Number n/a Related CAS Molecular Formula C36H52N4O9S Molecular Weight 716

525 SMILES OCCOCCOCCOCCOCCCC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Phthalimidinoglutarimide-propargyl-C1-OH deuterium-labeled-carboxylic ester 95 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCOCCOCCOCCOCCOCCOCCO)C(C)(C)C)C=C1 Purity (HPLC)Degrader building block for targeted protein degradation. Contains an E3 ligase ligand with a linker and a function group, which can be conjugated to target protein ligands through straightforward chemical reactions. Product Name Phthalimidinoglutarimide propargyl C1 OH Synonyms Phthalimidinoglutarimide 4' propargyl C1 OH CAS Number 2207541 23 7 Related CAS Molecular Formula C17H16N2O4 Molecular Weight 312. 325 SMILES