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75 Strikingly, transplantation of the gut microbiota from wild-type mice to AD mice alleviates the A load, neurofibrillary tangles and glial reactivity

Trained immunity is activated by PAMPs such as LPS or -glucan via PRR signaling, resulting changes in transcription programs through epigenetic regulation that can persist for up to several weeks (125, 126)

Describing nearly two decades of chagas disease in Germany and the lessons learned: a retrospective study on screening, detection, diagnosis, and treatment of trypanosoma cruzi infection from 2000-2018