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All those mechanisms are depicted in Figures 2A,B

The SCN receives light input directly from the retina and conveys time-of-day signals to peripheral clocks throughout the body, ensuring systemic synchronization ( At the molecular level, circadian rhythms are primarily driven by transcriptional-translational feedback loops (TTFLs) and rhythmic posttranslational modifications, such as phosphorylation and ubiquitination (Mendoza-Viveros et al., 2017)

In this formula, glutathione is wrapped in tiny fat bubbles called liposomes