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In addition, the increase in proinflammatory cytokines leads to the formation of fibrin amyloid microclot resistant to fibrinolysis, either by increased production of serum amyloid A (SAA) or by the release of -amyloid (A) peptide by platelets, resulting in capillary obstruction (156159)

10.12047/j.cjap.6229.2022.029 262 ZhaoH.ChenR.ZhengD.XiongF.JiaF.LiuJ.et al (2022b)

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Semaglutide is a modified analog designed to last much longer in the body