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Jordan B, Jahn F, Beckmann J, Unverzagt S, Muller-Tidow C, Jordan K

doi: 10.1136/ard.2011.149849 250 ZhaoMWangLWangMZhouSLuYCuiHet al

Safety of non-steroidal anti-inflammatory drugs, including aspirin and paracetamol (acetaminophen) in people receiving methotrexate for inflammatory arthritis (rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, other spondyloarthritis)

3,4 MMA is caused by disorders of methylmalonyl-CoA mutase (MCM) or cobalamin metabolism and is characterized by the abnormal accumulation of propionylcarnitine (C3), methylmalonic acid, methylcitrate (MCA) and other metabolites, which often leads to multiorgan damage